The 23-year-old sustained the injury in the 1-0 home defeat to Stevenage on Saturday, causing his half-time withdrawal.
He is now set to miss Wanderers' next four fixtures, which see them travel to Shrewsbury and Morecambe before hosting Stockport and then making the trip to Hereford.
Lewis has been a regular in the Wycombe team since joining permanently in January on an 18-month deal from Dagenham and Redbridge, making 11 appearances and netting two goals, both of which came in the 4-1 win over Burton on February 22.
Source: PA
Source: PA