Lewis has been ruled out for up to three weeks with ankle ligament damage sustained in the 1-0 home defeat to Stevenage last Saturday, so Lewis Montrose or Scott Donnelly will come into the side.
On-loan Watford defender Rob Kiernan is fit again after undergoing intensive treatment on a hip injury and will be involved.
Left-back Andy Sandell is still sidelined with a knee problem that is expected to keep him out for a minimum of six weeks, so Danny Foster will continue.
The Shrews will close to within a point of the Chairboys with a win so Gary Waddock's side need a result to put their promotion charge back on track.
Source: PA
Source: PA