Shaun Miller's ninth goal of the season early in the second half set the Shrimps on their way before Jamie Devitt scored from the spot late on after goalkeeper Matt Ingram was sent off
The result was the Chairboys' first defeat in six contests in all competitions and ended their three-match winning run
The first half was uneventful, with the only really chance seeing a free-kick from Morecambe's Kevin Ellison tipped round the post by Ingram
Both teams came out with more attacking intent in the second half and Morecambe took the lead in the 54th minute when Miller scrambled in Ellison's header from Devitt's long ball
The points were effectively secured when substitute Aaron Wildig was brought down by Ingram and he was given his marching orders
Defender Jason McCarthy - whose loan from Southampton is due to expire on Sunday - went in goal and, although he went the right way, Devitt's penalty was too powerful
Source : PA
Source: PA